However, differences in the exact way of measuring this space result in clinically significant different results and, therefore, debate remains about the true value of this measured parameter.Ĭopyright © 2023, StatPearls Publishing LLC. The anatomical dead space is the total volume of the conducting airways from the nose or mouth to the terminal bronchioles, and in ventilated infants includes the apparatus dead space (endotracheal tube and flow sensor). Indeed, it may serve as a prognostic factor in patients with acute repository distress syndrome (ARDS) who require ventilation. The physiological dead space is the anatomical dead space plus alveolar dead space. This phenomenon has clinical significance because, both in healthy and impaired lungs, properly calculating and accounting for this non-physiological space is important for the proper respiratory care of ventilated patients. This is therefore termed anatomical dead space as it serves no respiratory function. Anatomic dead space is an important phenomenon in respiratory physiology whereby, owing to the fact that upper airways do not function as locations for gas exchange, and because of the tidal nature of ventilation, there is always a fraction of the inspired air that does not perform a physiologic function of exchanging carbon dioxide for oxygen.
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